Dr. Wilson’s New R01 Grant

Persons infected with HIV now have a life expectancy that approaches that of the general population, but they remain at a significantly elevated risk of developing cognitive impairments. Recent neuroimaging studies have identified the cortical brain circuits that are centrally involved in these generally mild cognitive impairments, but the underlying molecular mechanisms remain poorly understood, and the potential therapeutic options are very limited. In April 2022, Dr. Tony W. Wilson of the Dynamic Imaging of Cognition and Neuromodulation (DICoN) Lab received a grant from the National Institute on Drug Abuse branch of the NIH to determine whether parameters of the mitochondrial redox environment drive neuro-inflammation in persons with HIV. This study also explores whether chronic cannabis use modulates these parameters, with the long-term goal of identifying viable therapeutics for persons with HIV.

To learn more about Dr. Wilson’s project, please visit NIH Reporter.